BLOOD COAGULATION INDICATORS’ CHARACTERISTICS EXAMINED IN PATIENTS WITH LIVER CIRRHOSIS AT TRA VINH GENERAL HOSPITAL, VIETNAM

Abstract

The objective of the study is to investigate the characteristics of several coagulation indices in patients with cirrhosis at Tra Vinh
General Hospital, Vietnam. The cross-sectional study used retrospective data in the medical records of 171 patients with cirrhosis at Tra Vinh General Hospital from January 2023 to August 2024. The results showed that patients with cirrhosis had an average prothrombin time value of 58.85±19.53%, an average activated partial thromboplastin time of 33.04±8.06 seconds, and an average international normalized ratio of 1.48±0.40. Of which, the rate of prothrombin time reduction < 70% accounted for 74.27%. At the same time, the study found a correlation between prothrombin time reduction < 70%, activated partial thromboplastin time prolongation > 40 seconds, and international normalized ratio > 1.4 with the stage of decompensated cirrhosis. Thus, in the treatment of cirrhosis, clinicians must pay attention to cases with prothrombin time reduction < 70%, activated partial thromboplastin time > 40 seconds, and international normalized ratio > 1.4, because patients with decompensated cirrhosis often have the above blood count characteristics.