RELATIONSHIP BETWEEN SERUM IRON AND CHARACTERISTICS SOCIAL POPULATION IN PATIENTS WITH HELICOBACTER PYLORI INFECTION
Abstract
The objective of the study is to investigate the value of serum iron index in patients infected with Helicobacter pylori and find out the correlation between serum iron index and sociodemographic characteristics in patients infected with Helicobacter pylori at faculty 2 of University Medical Center Ho Chi Minh City. The study used CLO and HP CIM tests to determine the Helicobacter pylori infection status, and also collected the serum/plasma of the patient after the HP CIM test to investigate the serum iron index. The Stata 14.0 software was used to manage and analyse data, the ANOVA test was used to test for 3 means or more, and the Chi-squared test was
used to test the difference in proportions between groups. The results showed that the serum iron concentration in the patient group was 59,4±42,1 mg/dL lower than the serum iron value in the control group, which was 86,1±32,0 mg/dL (p < 0,001). The results also indicated that the serum iron value in patients infected with Helicobacter pylori decreased as compared to patients without infection, yet the study also found a relationship between age group and geographical factors. This difference is statistically significant with p <
0,001, p = 0,001, p = 0,04 and p = 0,001.
Downloads
References
Helicobacter pylori. Hà Nội: Nhà Xuất bản Y học;
2008. [Tran Thien Trung. Gastrointestinal diseases
and Helicobacter pylori infection. Hanoi: Medical
Publishing House; 2008].
[2] Bùi Hữu Hoàng. Cập nhật thông tin về Helicobacter
pylori. [Update on Helicobacter pylori information].
Tạp chí Y học Thành phố Hồ Chí Minh. 2009;13(1):
1109–1112. [Bui Huu Hoang. Update on Helicobacter pylori information. Medical Journal. 2009;13(1):
1109–1112].
[3] Durdi Qujeq, Maryam Sadogh, Shahreyar Savadkohi.
Association between Helicobacter pylori infection and
serum iron profile. Caspian J Intern Med. 2011;2(3):
266–269.
[4] Thái Quý, Nguyễn Hà Thanh. Huyết học và truyền
máu sau đại học. [Hematology and transfusion after
graduation]. [Giáo trình môn học]. Đại học Y Hà Nội.
2014. [Thai Quy, Nguyen Ha Thanh. Hematology and
transfusion after graduation. [Course textbook] Hanoi
Medical University. 2014].
[5] Cardenas VM, Mulla ZD, Ortiz M, Graham DY. Iron
deficiency and Helicobacter pylori infection in the
United States. American Journal of Epidemiology.
2006;163(2): 127–134.
[6] Saleh MA, Hassan EA. The relationship between
Helicobacter pylori and iron deficiency anemia. AlAzhar Assiut Medical Journal. 2015:13(3); 229–232.
[7] Enko D, Wagner H, Kriegshauser G, ¨ Wogerer ¨
J, Halwachs-Baumann G, Schnedl WJ, et al.
Iron status determination in individuals with
Helicobacter pylori infection. Clinical Chemistry
and Laboratory Medicine. 2019;57(7): 982–989.
https://doi.org/10.1515/cclm-2018-1182.
[8] Lê Trung Thọ, Trần Văn Hợp, Phạm Bình Nguyên.
Nghiên cứu mô bệnh học và tỷ lệ nhiễm Helicobacter
pylori ở bệnh nhân viêm dạ dày mạn tính. Tạp
chí Y học Thành phố Hồ Chí Minh. 2007;(11)3:
68–75. [Le Trung Tho, Tran Van Hop, Pham Binh
Nguyen. Study of histopathology and Helicobacter
pylori infection rate in patients with chronic gastritis.
Medical Journal. 2007;(11)3: 68–75].
[9] Tari K, Shamsi Z, Rahimi A, Atashi A. Relationship
between the serum ferritin and TIBC level and Heclicobacter pylori infection. Zahedan J Red Med Sci.
2016;18(8): e7935. DOI: 10.17795/zjrms-7935.
[10] Tseng DS, Li D, Cholleti SM, Wei JC, Jodesty Y,
Pham HV. Effect of Helicobacter pylori treatment
on unexplained iron deficiency anemia. Permanente
Journal. 2019;23(3): 18–25.
[11] Rahman YA, Ahmed LAW, Hafez RMM, Ahmed
RMM. Helicobacter pylori and its hematological effect. The Egyptian Journal of Internal Medicine.
2019;31: 332–342. DOI:10.4103/ejim.ejim_103_18
[12] Kishore G, Ejaz M, Kumar J, Lal A, Tahir H, Anjum
Z, et al. Association between Helicobacter pylori
infection and serum iron profile. Cureus. 2021;13(9):
e17925. DOI 10.7759/cureus.17925.
[13] Võ Thị Thái Sơn. Các yếu tố liên quan đến nhiễm
Helicobacter pylori ở người lớn. Luận văn Thạc sĩ.
Trường Đại học Y Dược Thành phố Hồ Chí Minh;
2018. [Vo Thi Thai Son. Factors related to Helicobacter pylori infection in adults. Master’s thesis. Ho
Chi Minh City University of Medicine and Pharmacy; 2018]
