APPLICATION OF CHITOSAN IN PAPER-BASED SENSOR FABRICATION FOR THE DETERMINATION OF ANTIOXIDANT ACTIVITY

Main Article Content

Duy The Phan
Triet Duy Anh Ngo

Abstract

Paper-based sensor is an innovation technology for fabricating simple, lowcost, portable and disposable analytical device for many application areas including clinical diagnosis, food quality control and environmental monitoring. It reports a simple yet sensitive multilayer sensor based on the colorimetric reaction between polyphenols and Fe3+. The sensor was fabricated by alternative assembly of a chitosan layer, Fe3+ complexes and an alginate sodium layer on filter
paper modified with a TiO2 layer. After five cycles repeated assembly, the obtained sensor achieved good hydrophobicity, and together with the specific affinity of chitosan, polyphenols in aqueous samples can be pre-concentrated on the surface of the sensor, leading to improvement of the sensor sensitivity. The  detection limits for model polyphenols gallic acid was 0.012 ppm with a wide linear range between 0,02 and 6.1 ppm. The colorimetric multilayer sensor was further applied to determine the antioxidant activity of red wine and green tea samples through the polyphenols content analysis. The sensor obtained here can
serve as a cheap and convenient for real-time quality analysis of the antioxidant products.

Downloads

Download data is not yet available.

Article Details

How to Cite
Phan, D. and Ngo, T. (2020) “APPLICATION OF CHITOSAN IN PAPER-BASED SENSOR FABRICATION FOR THE DETERMINATION OF ANTIOXIDANT ACTIVITY”, The Scientific Journal of Tra Vinh University, 1(3), pp. 88-95. Available at: http://journal.tvu.edu.vn/index.php/journal/article/view/230 (Accessed: 16April2021).
Section
Proceeding

References

[1] Akiyama H., Fujii K., Yamasaki O., Oono T.,
Iwatsuki K., “Antibacterial action of several tannins against Staphylococcus aureus”, J. Antimicrob.
Chemother., 2001, 48, 487–491.
[2] Alkasir R.S.J., Ornatska M., Andreescu S., “Colorimetric paper bioassay for the detection of phenolic
compounds”, Anal. Chem., 2012, 84, 9729–9737.
[3] Apak, K. Guc¸lu, B. Demirata, M. Ozyurek, S. E.
C¸ elik, B. Bektasoglu, K. I. Berker, D. Ozyurt, “Comparative evaluation of various total antioxidant capacity assays applied to phenolic compounds with the
CUPRAC assay”, Molecules, 2007, 12, 1496–1547.
[4] Arciuli M., Palazzo G., Gallone A., Mallardi A.,
“Bioactive paper platform for colorimetric phenols
detection”, Sens. Actuators B, 2013, 186, 557–562.
[5] Chen Z., Zhang X., Cao H., Huang Y., “Chitosancapped silver nanoparticles as a highly selective
colorimetric probe for visual detection of aromatic ortho-trihydroxy phenols”, Analyst, 2013, 138,
2343–2349.
[6] Fontana A. R., Bottini R., “High-throughput method
based on quick, easy, cheap, effective, rugged
and safe followed by liquid chromatography-multiwavelength detection for the quantification of multiclass polyphenols in wines”, J. Chromatogr. A, 2014,
1342, 44–53.
[7] Franquet-Griell H., Checa A., Nunez O., Saurina J.,
Hernandez-Cassou S., Puignou L., “Determination
of polyphenols in Spanish Wines by capillary zone
electrophoresis. Application to wine characterization
by using chemometrics”, J. Agric. Food Chem., 2012,
60, 8340–8349.
[8] Gamella M., Campuzano S., Reviejo A.J., Pingarron
J.M., “Electrochemical estimation of the polyphenol
index in wines using a laccase biosensor”, J. Agric.
Food Chem., 2006, 54, 7960–7967.
[9] George S., Brat P., Alter P., Amiot M. J., “Rapid
determination of polyphenols and vitamin C in plantderived products”, J. Agric. Food Chem., 2005, 53,
1370–1373.
[10] Hanif S., Shamim U., Ullah M.F., Azmi A. S., Bhat
S.H., Hadi S.M., “The anthocyanidin delphinidin mobilizes endogenous copper ions from human lymphocytes leading to oxidative degradation of cellular
DNA”, Toxicology, 2008, 249, 19–25.
[11] Huang J., Ichinose I., Kunitake T., “Biomolecular
modification of hierarchical cellulose fibers through
Titania nanocoating”, Angew. Chem., Int. Ed., 2006,
45, 2883–2886.
[12] Kallithraka S., M. I. Salacha, I. Tzourou, “Changes
in phenolic composition and antioxidant activity of
white wine during bottle storage: accelerated browing
test versus bottle storage”, Food Chem., 2009, 113,
500–505.
[13] Kuroda Y., Hara Y., “Antimutagenic and anticarcinogenic activity of tea polyphenols”, Rev. Mutat. Res.,
1999, 436, 69–97.
[14] Minussi R.C., Rossi M., Bologna L., Cordi L., Rotilio
D., Pastore G.M., Durán N., “Phenolic compounds
and total antioxidant potential of commercial wines”,
Food Chem., 2003, 82, 409–416.
[15] Nalewajko-Sieliwoniuk E., Tarasewicz I., Kojło A.,
“Flow injection chemiluminescence determination of
the total phenolics levels in plant-derived beverages
using soluble manganese (IV)”, Anal. Chim. Acta.,
2010, 668, 19–25.
[16] Ornatska M., Sharpe E., Andreescu D., Andreescu S.,
“Paper bioassay based on ceria nanoparticle as colorimetric probes”, Anal. Chem., 2011, 83, 4273–4280.
[17] Sanz V.C., Mena M. L., Gonzalez-Cortes A., YanezSedeno P., Pingarron J.M., “Development of a tyrosinase biosensor based on gold nanoparticles-modified
glassy carbon electrodes: application to the measurement of a bioelectrochemical polyphenols index in
wines”, Anal. Chim. Acta, 2005, 528, 1–8
[18] Shamim U., Hanif S., Ullah M.F., Azmi A.S., Bhat
S.H., Hadi S.M., “Plant polyphenols mobilize nuclear
copper in human peripheral lymphocytes leading to
oxidatively generated DNA breakage: Implications
for an anticancer mechanism”, Free Radic. Res.,
2008, 42, 764–772.
[19] Sharpe E., Bradley R., Frasco T., Jayathilaka D.,
Marsh A., Andreescu S., “Metal oxide based multisensory array and portable database for field analysis of antioxidants”, Sens. Actuators B, 2014, 193,
552–562.
[20] Souza L.P., Calegari F., Zarbin A.J.G., MarcolinoJunior L.H., Bergamini M.F., “Voltammetric determination of the antioxidant capacity in wine samples using a carbon nanotube modified electrode”, J.
Agric. Food Chem., 2011, 59, 7620–7625.
[21] Vaher M., Kaljurand M., “The development of paper
microzone-based green analytical chemistry methods for determining the quanlity of wines”, Anal.
Bioanal. Chem., 2012, 404, 627–633.
[22] Wang S., Ge L., Song X., Yu J., Ge S., Huang J., Zeng
F., “Paper-based chemiluminescence ELISA: lab-onpaper based on chitosan modified paper device and
wax-screen-printing”, Biosens. Bioelectron., 2012,
31, 212–218.
[23] Zhang Y., Huang J., “Hierarchical nanofibrous silicon as replica of natural cellulose substance”, J.
Mater. Chem., 2011, 21, 7161–7165.